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JoVE Journal Neuroscience
Voll- versus subregionale Quantifizierung der Amyloid-Beta-Belastung von Hirnschnitten der Maus
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Voll- versus subregionale Quantifizierung der Amyloid-Beta-Belastung von Hirnschnitten der Maus

Article DOI: 10.3791/63669-v • 07:28 min • May 19th, 2022
May 19th, 2022 •
1, 2, 3, 4, 4,5
1Henry E. Riggs School of Applied Life Sciences, Keck Graduate Institute, 2Crean College of Health and Behavioral Sciences, Chapman University, 3Keck Science Department, Claremont McKenna College, 4Department of Biomedical and Pharmaceutical Sciences, School of Pharmacy, Chapman University, 5Department of Neurology, University of California, Irvine

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Das vorliegende Protokoll beschreibt und vergleicht das Verfahren zur Durchführung einer Analyse der gesamten Region oder Subregion von Interesse an sagittalen Hirnschnitten der Maus zur Quantifizierung der Amyloid-Beta-Belastung im transgenen APP/PS1-Mausmodell der Alzheimer-Krankheit.

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Neuroscience Ausgabe 183
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