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JoVE Journal Neuroscience
Quantification complète ou sous-régionale de la charge bêta-amyloïde sur les sections cérébrales de souris
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Quantification complète ou sous-régionale de la charge bêta-amyloïde sur les sections cérébrales de souris

Article DOI: 10.3791/63669-v • 07:28 min • May 19th, 2022
May 19th, 2022 •
1, 2, 3, 4, 4,5
1Henry E. Riggs School of Applied Life Sciences, Keck Graduate Institute, 2Crean College of Health and Behavioral Sciences, Chapman University, 3Keck Science Department, Claremont McKenna College, 4Department of Biomedical and Pharmaceutical Sciences, School of Pharmacy, Chapman University, 5Department of Neurology, University of California, Irvine

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Le présent protocole décrit et compare la procédure permettant d’effectuer une analyse complète de région ou de sous-région d’intérêt de sections cérébrales de souris sagittales afin de quantifier la charge bêta-amyloïde dans le modèle murin transgénique APP/PS1 de la maladie d’Alzheimer.

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Neurosciences numéro 183
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