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Lethality Bioassay Using Artemia salina L.
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JoVE Journal Chemistry
Lethality Bioassay Using Artemia salina L.

Lethality Bioassay Using Artemia salina L.

DOI:
10.3791/64472-v

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09:09 min

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October 11, 2022

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, , , , ,
1CBIOS – Lusófona University’s Center for Research in Biosciences & Health Technologies,Universidade Lusófona de Humanidades e Tecnologias, 2Facultad de Farmacia, Departamento de Ciencias Biomédicas (Área de Farmacologia; Nuevos agentes antitumorales, Acción tóxica sobre células leucémicas),Universidad de Alcalá de Henares, 3Instituto de Investigação do Medicamento (iMed.ULisboa),Faculdade de Farmácia da Universidade de Lisboa

Chapters

  • 00:04Introduction
  • 01:21Equipment Preparation
  • 02:15Preparation of the Artificial Salt Solution and the Sample
  • 03:26Brine Shrimp Lethality Bioassay
  • 06:44Results: Lethality Evaluation of the Selected Pure Compounds and Extracts on Artemia salina
  • 08:17Conclusion

Summary

Automatic Translation

Automatic Translation

This work aims to evaluate and review the Artemia salina lethality bioassay procedure, also identified as brine shrimp lethality assay. This simple and cheap method gives information about the general toxicity (considered as a preliminary toxicity evaluation) of samples, namely, natural products.

Tags

Keywords: Lethality BioassayArtemia Salina L.Toxicity EvaluationNatural Or Synthetic SourcesScreeningPreliminary General ToxicityCell LinesIn-vivo TestsMedicinal And Other Products ChemistryNanosystemsHandmade Migration EquipmentArtificial Salt SolutionBrine Shrimp SaltDMSOPotassium Dichromate

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