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JoVE Journal Neuroscience
Vurdering af ændringer i synaptisk plasticitet ved hjælp af en vågen lukket hovedskademodel af mild traumatisk hjerneskade
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Vurdering af ændringer i synaptisk plasticitet ved hjælp af en vågen lukket hovedskademodel af mild traumatisk hjerneskade

Article DOI: 10.3791/64592-v • 09:49 min • January 20th, 2023
January 20th, 2023 •
1,2, 1, 1, 1, 1, 1, 1, 1, 1
1Division of Medical Sciences, University of Victoria, 2Island Medical Program, University of British Columbia

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Her demonstreres det, hvordan en vågen lukket hovedskademodel kan bruges til at undersøge effekterne af gentagen mild traumatisk hjerneskade (r-mTBI) på synaptisk plasticitet i hippocampus. Modellen replikerer vigtige træk ved r-mTBI hos patienter og bruges sammen med in vitro elektrofysiologi.

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Neurovidenskab udgave 191
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