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Un modelo de ratón de silicosis establecido por inhalación repetida de polvo de sílice cristalina
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Un modelo de ratón de silicosis establecido por inhalación repetida de polvo de sílice cristalina

Article DOI: 10.3791/64862-v • 10:45 min • January 6th, 2023
January 6th, 2023 •
*1,2,3,4, *1,2,3,4, 1,3,4, 1,4, 1,4, 1,4, 1,2,3,4, 1,2,3,4
1Key Laboratory of Industrial Dust Control and Occupational Health of the Ministry of Education, Anhui University of Science and Technology, 2Key Laboratory of Industrial Dust Deep Reduction and Occupational Health and Safety of Anhui Higher Education Institutes, Anhui University of Science and Technology, 3Anhui Province Engineering Laboratory of Occupational Health and Safety, 4School of Medicine, Department of Medical Frontier Experimental Center, Anhui University of Science and Technology
* These authors contributed equally

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Este protocolo describe un método para establecer un modelo de ratón de silicosis a través de la exposición repetida a suspensiones de sílice a través de un goteo nasal. Este modelo puede imitar de manera eficiente, conveniente y flexible el proceso patológico de la silicosis humana con alta repetibilidad y economía.

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Medicina Número 191 Modelo de ratón Inhalación Fisiopatología Detección Tratamiento Síntomas clínicos Proceso de transformación agudo/crónico Procedimientos Polvo de CSD Suspensión salina Baño de agua ultrasónico Anestesia Aspiración Inhalación de fosas nasales Jaula de ratón
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