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Generering af Subkutan og Intrahepatisk Menneskelige hepatocellulært carcinom xenotransplantater i immunsvækkede mus
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Generering af Subkutan og Intrahepatisk Menneskelige hepatocellulært carcinom xenotransplantater i immunsvækkede mus

Article DOI: 10.3791/50544-v • 10:35 min • September 25th, 2013
September 25th, 2013 •
1, 1, 1, 1, 1, 2, 3, 1,3
1Toronto General Research Institute, University Health Network, 2Department of Pathology, University Health Network, 3Division of General Surgery, University Health Network

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Menneskelige tumorxenoplantater i immunsvækkede mus er værdifulde værktøjer til at studere kræft biologi. Særlige protokoller til at generere subkutane og intrahepatiske xenotransplantater fra humane levercellecancer celler eller tumor fragmenter er beskrevet. Lever regenerering fremkaldt ved delvis hepatektomi i recipientmus præsenteres som en strategi for at lette intrahepatisk engraftment.

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Medicine Lever neoplasmer hepatectomy dyremodeller hepatocellulært carcinom xenograft cancer lever subkutan intrahepatisk orthotopisk mus menneske immundefekte
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