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Journal / Cancer Research / Merking av brystkreftpasient-avledet xenografter…
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Cancer Research

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JoVE Journal Cancer Research
Merking av brystkreftpasient-avledet xenografter med Spor Reporters for tumorvekst og metastase Studier
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Journal (Cancer Research)
A Melanoma Patient-Derived Xenograft Model
Assessment of Chimeric Antigen Receptor T Cell-Associated Toxicities Using an Acute Lymphoblastic Leukemia Patient-Derived Xenograft Mouse Model
Journal (Cancer Research)
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Merking av brystkreftpasient-avledet xenografter med Spor Reporters for tumorvekst og metastase Studier

Article DOI: 10.3791/54944-v • 09:53 min • November 30th, 2016
November 30th, 2016 •
1, 1, 1, 1, 1
1Department of Pathology, School of Medicine, University of Colorado Anschutz Medical Campus

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Vi beskriver en metode for stabil merking av pasient avledet xenografter (PDXs) med lentiviral partikler uttrykker grønt fluorescerende protein og luciferase journalister. Denne metoden gjør det mulig for sporing vekst av PDXs på det primære stedet, samt å oppdage spontane og eksperimentelle metastaser ved hjelp av in vivo imaging-systemer.

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Cancer Research PDX Pasient-avledet-xenografter lentiviral luciferase transplantasjon musemodeller metastase
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