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In Vitro Enzym målingen Test farmakologiske Anstandsdame hastighet i Fabrys og Pompe sykdom

Article DOI: 10.3791/56550-v • 10:16 min • December 20th, 2017
December 20th, 2017 •
1, 1, 1, 2, 2, 1,3
1Albrecht-Kossel-Institute, University Rostock Medical Center, 2Department of Biology, University Federico II, 3Centogene AG

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Det er et behov å pre-klinisk testing av en roman klasse av "linjer" legemidler kalt farmakologiske chaperones reproduserbare, rask og effektiv. Vi utviklet en enkel, svært standardisert og allsidig celle kultur-baserte analysen til skjermen for kvalifisert pasienter samt romanen farmakologiske Anstandsdame narkotika.

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Medisin problemet 130 lysosomale lagring lidelse fenotype glycosidase små molekyl narkotika preklinisk test personlig terapi
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