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Journal / Medicine / Gestandaardiseerde meting van nasale membraan…
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Gestandaardiseerde meting van nasale membraan Transepithelial potentieel verschil (NPD)
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Gestandaardiseerde meting van nasale membraan Transepithelial potentieel verschil (NPD)

Article DOI: 10.3791/57006-v • 09:47 min • September 13th, 2018
September 13th, 2018 •
1, 2, 3, 4, 5, 1, 6,7
1Department of Medicine and the Gregory Fleming James Cystic Fibrosis Center, University of Alabama at Birmingham, 2Department of Pulmonology and Tuberculosis, University Medical Center Utrecht, 3Center for Experimental Medicine, Queens University, Northern Ireland, 4Hadassah Hebrew University Medical Center, Jerusalem, 5Centro Fibrosi Cistica, Azienda Ospedaliera Universitaria Integrata, 6Service de Pneumologie et Allergologie Pédiatriques and Center de Ressources et de Compétence de la Mucoviscidose, Hôpital Necker Enfants Malades, 7INSERM U 1151, Institut Necker Enfants Malades

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Hier presenteren we een gestandaardiseerd protocol voor het meten van de nasale potentiaalverschil (NPD). Cystic fibrosis transmembrane huidgeleiding regelgever (CFTR) en epitheliale natrium kanaal (ENaC) functie worden geëvalueerd door de verandering in de spanning over de nasale epitheel na superfusion van oplossingen die ion kanaal activiteit, wijzigen mits een resultaat maatregel.

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Geneeskunde kwestie 139 nasale potentiaalverschil Cystic Fibrosis Cystic Fibrosis Transmembrane huidgeleiding Regulator CFTR
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