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Rat Intestinal Crypts Isolation and Intestinal Organoids Generation

June 23rd, 2023
*1, *1,2, 3,4, 1,5,6
1Department of Genetics, Yale School of Medicine, 2Department of Pediatrics, Yale School of Medicine, 3Department of Pediatrics/Gastroenterology and Hepatology, Yale School of Medicine, 4Department of Cellular and Molecular Physiology, Yale School of Medicine, 5Yale Stem Cell Center, Yale School of Medicine, 6Yale Cancer Center, Yale School of Medicine
* These authors contributed equally

Summary
Automatic Translation

Her præsenterer vi en protokol til generering af rottetarmorganoider og bruger dem i flere downstream-applikationer. Rotter er ofte en foretrukken præklinisk model, og det robuste tarmorganoidsystem udfylder behovet for et in vitro-system til at ledsage in vivo-undersøgelser .

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