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Creating a Versatile Experimental Autoimmune Encephalomyelitis Model Relevant for Both Male and Female Mice (Video) | JoVE
Preparation of MOG35-55 Emulsion for Immunization of Mouse (Video) | JoVE
Immunization of Mouse with MOG35-55 to Induce Experimental Autoimmune Encephalomyelitis (Video) | JoVE
Clinical Score and Motor Performance Evaluation of Mouse Induced with Experimental Autoimmune Encephalomyelitis (Video) | JoVE
实验性自身免疫性脑脊髓炎是多发性硬化症使用最广泛的小鼠模型之一。在目前的方案中,两性的C57BL / 6J小鼠都用髓鞘少突胶质细胞糖蛋白肽免疫,主要导致尾巴和四肢的上行麻痹。在这里,我们讨论EAE诱导和评估的协议。
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