Induction and Evaluation of Experimental Autoimmune Encephalomyelitis in Mouse

October 13th, 2023

Creating a Versatile Experimental Autoimmune Encephalomyelitis Model Relevant for Both Male and Female Mice (Video) | JoVE

02:08 min

•

Preparation of MOG35-55 Emulsion for Immunization of Mouse (Video) | JoVE

01:01 min

•

Immunization of Mouse with MOG35-55 to Induce Experimental Autoimmune Encephalomyelitis (Video) | JoVE

00:56 min

•

Clinical Score and Motor Performance Evaluation of Mouse Induced with Experimental Autoimmune Encephalomyelitis (Video) | JoVE

01:52 min

•

Brigitta Bonaldo^1,2, Antonino Casile^1,2,3, Francesca Montarolo^1,2, Antonio Bertolotto^1,4

¹Neuroscience Institute Cavalieri Ottolenghi (NICO), ²Department of Neuroscience “Rita Levi-Montalcini”, University of Turin, ³School of Pharmacy, Pharmacology Unit, University of Camerino, ⁴Koelliker Hospital

Summary
Automatic Translation

English (Original)
العربية (Arabic)
中文 (Chinese)
dansk (Danish)
Nederlands (Dutch)
français (French)
Deutsch (German)
עברית (Hebrew)
हिंदी (Hindi)
italiano (Italian)
日本語 (Japanese)
한국어 (Korean)
norsk (Norwegian)
português (Portugese)
русский (Russian)
español (Spanish)
svenska (Swedish)
Türkçe (Turkish)

실험적 자가면역 뇌척수염은 다발성 경화증에서 가장 널리 사용되는 쥐 모델 중 하나입니다. 현재 프로토콜에서는 남녀 모두의 C57BL/6J 마우스에 미엘린 희소돌기아교세포 당단백질 펩타이드를 면역하여 주로 꼬리와 팔다리의 상행 마비를 초래합니다. 여기서는 EAE 유도 및 평가 프로토콜에 대해 논의합니다.

Article

Induction and Evaluation of Experimental Autoimmune Encephalomyelitis in Mouse

Get cutting-edge science videos from JoVE sent straight to your inbox every month.