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扩展轴突转运体内成像工具包

Expanding the Toolkit for <em>In Vivo</em> Imaging of Axonal Transport

JoVE 杂志
神经科学

This content is Free Access.

JoVE 杂志神经科学

Expanding the Toolkit for In Vivo Imaging of Axonal Transport

扩展轴突转运体内成像工具包

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3,379 Views

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09:24 min

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December 23, 2021

DOI:

10.3791/63471-v

DOI:

10.3791/63471-v

•

09:24 min

December 23, 2021

•

3357 Views

Andrew P. Tosolini^1,2, David Villarroel-Campos^1,2,3, Giampietro Schiavo^1,2,3, James N. Sleigh^1,2,3

¹Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology,University College London ²UCL Queen Square Motor Neuron Disease Centre,University College London ³UK Dementia Research Institute,University College London

Summary

使用转基因荧光小鼠，描述了详细的方案，以评估活体动物完整坐骨神经的运动和感觉轴突内信号内体和线粒体的体内轴突转运。

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