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Laserablasjon og intravital mikroskopi for å studere intestinal remodellering
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Laserablasjon og intravital mikroskopi for å studere intestinal remodellering

Article DOI: 10.3791/64756-v • June 9th, 2023
June 9th, 2023 •
*1,2, *1,2, 3, 3, 1,2, 1,2
1Department of Molecular Pathology, The Netherlands Cancer Institute, 2Oncode Institute, 3Animal Laboratory Facility, The Netherlands Cancer Institute
* These authors contributed equally

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Her presenterer vi en metode for å få bilder av tarmen ved laserindusert sår. Ved å utsette musetarmen for en multifotonlaser, induseres tapet av en enkelt eller flere krypter lokalt. Ved å gjentatte ganger avbilde det skadede området over måneder, fanges sanntidsdynamikken i tarmutvinning.

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Biologi laser ablation intravital mikroskopi tarm regenerering skade krypt remodeling
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