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JoVE Journal Cancer Research
Spontaan muizenmodel van anaplastische schildklierkanker
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Spontaan muizenmodel van anaplastische schildklierkanker

Article DOI: 10.3791/64607-v • 05:39 min • February 3rd, 2023
February 3rd, 2023 •
1, 1, 2, 3, 2, 4, 5, 1,6, 2,6
1State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, 2Division of Thyroid Surgery, Laboratory of Thyroid and Parathyroid Disease, Frontiers Science Center for Disease-Related Molecular Network, Department of General Surgery, West China Hospital, Sichuan University, 3Department of Ultrasound, West China Hospital of Sichuan University, Sichuan University, 4Department of Otolaryngology-Head & Neck Surgery and University of Arizona Cancer Center, University of Arizona, 5Center for Translational Medicine, Shenzhen Bay Laboratory, 6Division of Laboratory Medicine/Research Centre of Clinical Laboratory Medicine, West China Hospital, Sichuan University

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Hier presenteren we een standaard pijplijn om murine ATC-tumoren te verkrijgen door spontane genetisch gemanipuleerde muismodellen. Verder presenteren we tumordynamiek en pathologische informatie over de primaire en uitgezaaide laesies. Dit model zal onderzoekers helpen om tumorigenese te begrijpen en medicijnontdekkingen te vergemakkelijken.

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Cancer Research Nummer 192
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