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Ultrahigh opløsning musen optisk kohærens tomografi til støtte intraokulært injektion i Retinal genterapi forskning

Article DOI: 10.3791/55894-v • 10:10 min • November 2nd, 2018
November 2nd, 2018 •
1,2, 1,2,3,4,5,6,7
1Research Service, VA Western New York Healthcare System, 2Department of Ophthalmology, (Ross Eye Institute), Jacobs School of Medicine and Biomedical Sciences, University at Buffalo- SUNY, 3Pharmacology/Toxicology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo- SUNY, 4Physiology/Biophysics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo- SUNY, 5Neuroscience Program, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo- SUNY, 6The RNA Institute, University at Buffalo- SUNY, 7The SUNY Eye Institute

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Her viser vi en ny tilgang til at bruge høj opløsning spektral-domæne optisk kohærens tomografi (HR-SD-OCT) at hjælpe levering af genet terapi agenter ind i subretinal rummet, vurdere dens areal dækning og karakterisere fotoreceptor vitalitet.

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Medicin sag 141 optisk kohærens tomografi Retinal Degeneration Greenough Stereo mikroskopi Imaging intraokulært injektion In Vivo mikroskop fotoreceptorer prækliniske Real-time nethinden sub retinal.
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