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Cancer Research

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Na Vivo Avaliação de EPR de pH, pO2, Status Redox e as concentrações de fosfato e glutationa no microambiente do Tumor

Article DOI: 10.3791/56624-v • 10:46 min • March 16th, 2018
March 16th, 2018 •
1,2, 1,3, 1,2, 1,2
1In Vivo Multifunctional Magnetic Resonance center, Robert C. Byrd Health Sciences Center, West Virginia University, 2Department of Biochemistry, West Virginia University School of Medicine, 3Department of Microbiology, Immunology & Cell Biology, West Virginia University School of Medicine

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Baixo-campo (L-band, 1.2 GHz) ressonância paramagnética electrónica utilizando sondas de nitroxyl e trityl solúveis é demonstrada para avaliação dos parâmetros fisiologicamente importantes no microambiente do tumor em modelos do rato do cancro da mama.

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Cancer Research edição 133 ressonância paramagnética electrónica nitroxide trityl radical pH concentração de oxigênio status de redox glutationa fosfato inorgânico microambiente do tumor
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