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Single Myofiber isolering och kultur från en Murine modell av Emery-Dreifuss muskeldystrofi i tidig postnatal utveckling
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Single Myofiber isolering och kultur från en Murine modell av Emery-Dreifuss muskeldystrofi i tidig postnatal utveckling

Article DOI: 10.3791/61516-v • 08:07 min • July 1st, 2020
July 1st, 2020 •
1,2, 1,2, 3, 1,2,4
1Istituto Nazionale di Genetica Molecolare "Romeo ed Enrica Invernizzi", 2IRCCS Santa Lucia Foundation, 3Department of Biology and Biotechnology, "C. Darwin" Sapienza University, CNR - IBPM, 4CNR – Institute of Biomedical Technologies (ITB)

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Här föreslår vi en metod för att effektivt få enstaka muskelfibrer i tidiga postnatala utvecklingsstadier från homozygous mutant Lamin Δ8-11 mus modell, en mycket svår modell för Emery-Dreifuss muskeldystrofi (EDMD).

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Medicin Emery-Dreifuss muskeldystrofi musmodell myofiber immunofluorescens satellitmuskelstamceller differentiering muskelregenerering
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