Waiting
로그인 처리 중...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Medicine / MRI-guided Disruption of the Blood-brain Barrier…
JoVE Journal
Medicine

JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다.

JoVE Journal Medicine
MRI-guided Disruption of the Blood-brain Barrier using Transcranial Focused Ultrasound in a Rat Model
A Model of Long-Term Ventricular Fibrillation in Isolated Rat Hearts
Journal (Medicine)
A Model of Long-Term Ventricular Fibrillation in Isolated Rat Hearts
Isolation of Cancer Stem Cells From Human Prostate Cancer Samples
Journal (Medicine)
Isolation of Cancer Stem Cells From Human Prostate Cancer Samples
 

MRI-guided Disruption of the Blood-brain Barrier using Transcranial Focused Ultrasound in a Rat Model

Article DOI: 10.3791/3555-v • 07:43 min • March 13th, 2012
March 13th, 2012 •
1, 1,2, 1,2, 1,3
1Imaging Research, Sunnybrook Research Institute, 2Department of Medical Biophysics, University of Toronto, 3Department of Medical Biophysics, and Institute of Biomaterials & Biomedical Engineering (IBBME), University of Toronto

챕터

요약
Automatic Translation

Microbubble-mediated focused ultrasound disruption of the blood-brain barrier (BBB) is a promising technique for non-invasive targeted drug delivery in the brain1-3. This protocol outlines the experimental procedure for MRI-guided transcranial BBB disruption in a rat model.

Tags

MRI-guided Disruption Blood-brain Barrier Transcranial Focused Ultrasound Rat Model FUS Pharmaceutical Treatments Brain Disorders Molecules Vasculature Size Temporary Reversible Chemical Means Localized Therapeutic Agents Concentration Ultrasound Parameters Experimental Procedure Accurate Targeting Animal Preparation Microbubble Handling
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter