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Un modèle de rat Sprague Dawley d’ostéosarcome orthotopique syngénique avec amputation pour contrôler le taux de métastases

Article DOI: 10.3791/62139-v • 07:31 min • May 3rd, 2021
May 3rd, 2021 •
1,2,3,4, 5, 1, 6, 7, 8, 9, 10, 4, 1,2
1Department of Molecular and Comparative Pathobiology, The Johns Hopkins University School of Medicine, 2Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, 3Department of Surgery, Johns Hopkins University School of Medicine, 4Department of Coloproctological Surgery, Juntendo University Faculty of Medicine, 5Program for Comparative Medicine, Gene Therapy Program, Perelman School of Medicine, University of Pennsylvania, 6Tuskegee College of Veterinary Medicine, 7Department of Human Pathology, Juntendo University Faculty of Medicine, 8Department of Surgery, Juntendo University Shizuoka Hospital, Juntendo University School of Medicine, 9Department of Urology, The Johns Hopkins School of Medicine, 10Department of Gastroenterology and Minimally Invasive Surgery, Juntendo University Faculty of Medicine

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Ici, une implantation orthotopique syngénique suivie d’une procédure d’amputation de l’ostéosarcome avec métastases pulmonaires spontanées pouvant être utilisée pour l’investigation préclinique de la biologie des métastases et le développement de nouvelles thérapies est décrite.

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Recherche sur le cancer numéro 171 sarcome ostéosarcome implantation orthotopique modèle de rat syngénique métastases pulmonaires amputation de la jambe imagerie aux rayons X
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