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Neurocircuit Assays for Seizures in Epilepsy Mutants of Drosophila
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Neurocircuit Assays for Seizures in Epilepsy Mutants of Drosophila

Neurocircuit Assays for Seizures in Epilepsy Mutants of Drosophila

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10,324 Views

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09:11 min

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April 15, 2009

DOI:

10.3791/1121-v

DOI:
10.3791/1121-v

•

09:11 min
April 15, 2009

•

9 Views
,
1Department of Molecular and Cell Biology,University of California, Berkeley, 2Department of Environmental Science, Policy Management,University of California, Berkeley

Summary

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Using high frequency electrical stimulation, seizure-like activity can be induced in Drosophila. This activity is easily recorded from the giant fiber system.

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Neurocircuit AssaysSeizuresEpilepsy MutantsDrosophila MelanogasterSeizure-like ActivityPhysical ShockElectrical StimulationGenotypeSeizure ThresholdDrug TreatmentGenetic SuppressionGenetic EnhancementElectrophysiologyHigh Frequency Electrical StimulationDorsal Longitudinal Muscles (DLMs)Giant Fiber System

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Cite this Article

Howlett, I. C., Tanouye, M. A. Neurocircuit Assays for Seizures in Epilepsy Mutants of Drosophila. J. Vis. Exp. (26), e1121, doi:10.3791/1121 (2009).

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