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Neurocircuit Assays for Seizures in Epilepsy Mutants of Drosophila
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Neurocircuit Assays for Seizures in Epilepsy Mutants of Drosophila

Neurocircuit Assays for Seizures in Epilepsy Mutants of Drosophila

DOI:
10.3791/1121-v

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09:11 min

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April 15, 2009

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,
1Department of Molecular and Cell Biology,University of California, Berkeley, 2Department of Environmental Science, Policy Management,University of California, Berkeley

Chapters

  • 00:00Title
  • 00:55Introduction
  • 01:28Specimen Preparation
  • 03:05Electrophysiology Set Up
  • 05:20Making Recordings from the Giant Fiber Neuron
  • 08:11Representative Results/ Outcome
  • 08:38Conclusion

Summary

Automatic Translation

Automatic Translation

Using high frequency electrical stimulation, seizure-like activity can be induced in Drosophila. This activity is easily recorded from the giant fiber system.

Tags

Neurocircuit AssaysSeizuresEpilepsy MutantsDrosophila MelanogasterSeizure-like ActivityPhysical ShockElectrical StimulationGenotypeSeizure ThresholdDrug TreatmentGenetic SuppressionGenetic EnhancementElectrophysiologyHigh Frequency Electrical StimulationDorsal Longitudinal Muscles (DLMs)Giant Fiber System

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