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Bioengineering

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JoVE Journal Bioengineering
Fluorescent Nanoparticles for the Measurement of Ion Concentration in Biological Systems
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Fluorescent Nanoparticles for the Measurement of Ion Concentration in Biological Systems

Article DOI: 10.3791/2896-v • 08:17 min • July 4th, 2011
July 4th, 2011 •
1, 1, 2
1Bioengineering Department, Northeastern University, 2Department of Pharmaceutical Sciences, Northeastern University

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Fluorescent nanoparticles produced in our lab are used for imaging ion concentrations and ion fluxes in biological systems such as cells during signaling and interstitial fluid during physiological homeostasis.

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Fluorescent Nanoparticles Ion Concentration Biological Systems Ion Homeostasis Dehydration Rapid Ion Fluxes Cellular Level Action Potentials Sodium Regulation Monitoring Sodium Levels Intracellular Sodium Probes Calcium Probes Fluorescent Nanosensors Sodium Concentrations In Vitro In Vivo Ion-selective Optode Technology Plasticized Polymeric Particles Sodium Specific Recognition Elements PH-sensitive Fluorophores Additives Mechanism Of Action Change In Fluorescence Reversible Sensors Selective For Sodium Over Potassium Diameter Of Nanoparticles Biocompatibility
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