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Journal / Biology / Aviditet baseret ekstracellulær interaktion…
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Aviditet baseret ekstracellulær interaktion Screening (AVEXIS) for skalerbar detektion af lav affinitet Ekstracellulære Receptor-Ligand Interactions
Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
Journal (Biology)
Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
Identification of Protein Interacting Partners Using Tandem Affinity Purification
Journal (Biology)
Identification of Protein Interacting Partners Using Tandem Affinity Purification
 
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Aviditet baseret ekstracellulær interaktion Screening (AVEXIS) for skalerbar detektion af lav affinitet Ekstracellulære Receptor-Ligand Interactions

Article DOI: 10.3791/3881 • 12:30 min • March 5th, 2012
March 5th, 2012 •
1, 1
1Cell Surface Signalling Laboratory, Wellcome Trust Sanger Institute

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AVEXIS er et højt gennemløb protein-interaktion assay udviklet til systematisk screening for hidtil ukendte ekstracellulære receptor-ligand-par involveret i cellulære genkendelse processer. Det er specielt designet til at detektere transiente proteininteraktioner, der er vanskelige at identificere ved hjælp af andre højt gennemløb fremgangsmåder.

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Molecular Biology receptor-ligand-par ekstracellulært protein interaktioner AVEXIS adhæsionsreceptorer transient / svag interaktion High throughput screening
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