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JoVE Journal
Biology

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A Novel Bayesian Change-point Algoritme for genom-dækkende analyse af Diverse ChIPseq Datatyper
 
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A Novel Bayesian Change-point Algoritme for genom-dækkende analyse af Diverse ChIPseq Datatyper

Article DOI: 10.3791/4273
December 10th, 2012

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Summary December 10th, 2012

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Vores Bayesian Change Point (BCP) algoritme bygger på state-of-the-art fremskridt i modellering skift-point via Hidden Markov Models og anvender dem til chromatin immunoprecipitation sekventering (ChIPseq) dataanalyse. BCP klarer sig godt i både brede og punktformig datatyper, men excellerer i præcist at identificere robuste, reproducerbare øer af diffus histon berigelse.

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