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A Simple Stimulatory Device for Evoking Point-like Tactile Stimuli: A Searchlight for LFP to Spike Transitions
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Neuroscience
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JoVE Journal Neuroscience
A Simple Stimulatory Device for Evoking Point-like Tactile Stimuli: A Searchlight for LFP to Spike Transitions

A Simple Stimulatory Device for Evoking Point-like Tactile Stimuli: A Searchlight for LFP to Spike Transitions

DOI:
10.3791/50941-v

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07:34 min

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March 25, 2014

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, , , , ,
1Institute of Molecular Bioimaging and Physiology (IBFM), Department of Biomedicine,National Research Council, 2Institute of Biomedical Technologies (ITB), Department of Biomedicine,National Research Council, 3Faculty of Life Sciences,University of Manchester

Chapters

  • 00:05Title
  • 02:08Manufacture and Configuration of the Stimulation Device
  • 02:59Animal Preparation for Stereotaxic Surgery and Recording
  • 06:19Stimulation Protocol
  • 06:47Conclusion

Summary

Automatic Translation

Automatic Translation

To elucidate the complex transition from Local Field Potentials (LFPs) to spikes a suitable stimulator for light mechanical peripheral stimuli was built. As an application, the spiking activities recorded from somatosensory cortex were analyzed by a multi-objective optimization strategy. The results demonstrated that the proposed stimulator was able to deliver tactile stimuli with millisecond and millimeter precisions.

Tags

Keywords: Tactile StimuliLocal Field Potentials (LFPs)Spike ActivityNeural CodingDeep Brain StimulationMulti-objective OptimizationSomatosensory CortexPiezoelectric ActuatorsPredictive Models

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