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心肌梗死和功能预后评估的猪

JoVE Journal
Medicine

This content is Free Access.

JoVE Journal Medicine

Myocardial Infarction and Functional Outcome Assessment in Pigs

Please note that all translations are automatically generated. Click here for the English version.

心肌梗死和功能预后评估的猪

DOI:

10.3791/51269-v

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12:03 min

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April 25, 2014

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Stefan Koudstaal², Sanne J. Jansen of Lorkeers, Johannes M.I.H. Gho, Gerardus P.J van Hout, Marlijn S. Jansen, Paul F. Gründeman, Gerard Pasterkamp², Pieter A. Doevendans², Imo E. Hoefer*¹, Steven A.J. Chamuleau*¹

¹Department of Cardiology, Division Heart and Lungs,University Medical Center Utrecht, ²Interuniversity Cardiology Institute of the Netherlands

Chapters

00:05Title
02:02Transthoracic Echocardiography
02:56Surgical Preparation and Vascular Access
04:23Invasive Pressure Volume Loop Analysis
05:56Intracoronary Pressure and Flow Measurement
07:00Induction of Myocardial Infarction
08:58Results: Infarct Size, Cardiac Remodeling, and Cardiac Function
10:39Conclusion

Summary

Automatic Translation

本协议描述了猪心肌梗死（MI）模型中使用的左前降支（LAD）的90分钟闭胸冠状动脉球囊闭塞，再灌注。此外，该协议对于几个结果的参数，如心脏功能，血液动力学，微血管性和梗塞的大小，也被提出。

Tags

Keywords: Myocardial Infarction Porcine Model Closed-chest Coronary Balloon Occlusion Functional Outcome Assessment Cardiac Systolic And Diastolic Function Hemodynamics Coronary Flow Velocity Microvascular Resistance Infarct Size Cardioregenerative Biologics

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