Journal
/
/
Myocardial Infarction and Functional Outcome Assessment in Pigs
JoVE Journal
Medicine
This content is Free Access.
JoVE Journal Medicine
Myocardial Infarction and Functional Outcome Assessment in Pigs
DOI:

12:03 min

April 25, 2014

, , , , , , , , ,

Chapters

  • 00:05Title
  • 02:02Transthoracic Echocardiography
  • 02:56Surgical Preparation and Vascular Access
  • 04:23Invasive Pressure Volume Loop Analysis
  • 05:56Intracoronary Pressure and Flow Measurement
  • 07:00Induction of Myocardial Infarction
  • 08:58Results: Infarct Size, Cardiac Remodeling, and Cardiac Function
  • 10:39Conclusion

Summary

Automatic Translation

This protocol describes the porcine myocardial infarction (MI) model using a 90 min closed-chest coronary balloon occlusion of the left anterior descending artery (LAD), followed by reperfusion. Furthermore, the protocol for several outcome parameters, such as cardiac function, hemodynamics, microvascular resistance, and infarct size, are also presented.

Related Videos

Read Article