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JoVE Journal
Bioengineering

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Ordering Single Cells and Single Embryos in 3D Confinement
 

Ordering Single Cells and Single Embryos in 3D Confinement: A New Device for High Content Screening

Article doi: 10.3791/51880
September 18th, 2016

Summary September 18th, 2016

We report a device and a new method to study cells and embryos. Single cells are precisely ordered in microcavity arrays. Their 3D confinement is a step towards 3D environments encountered in physiological conditions and allows organelle orientation. By controlling cell shape, this setup minimizes variability reported in standard assays.

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