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JoVE Journal Biology
Utvärdering av Zebrafish njurfunktion med hjälp av en fluorescerande Clearance Assay
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Utvärdering av Zebrafish njurfunktion med hjälp av en fluorescerande Clearance Assay

Article DOI: 10.3791/52540
February 20th, 2015 •
1, 1, 2
1Genetics and Genomic Medicine, Institute of Child Health, University College London, 2Molecular Cell Science Research Centre, St. George's University of London

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February 20th, 2015

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Den zebrafisk är ett populärt verktyg för att modellera kronisk njursjukdom (CKD). Emellertid gör deras ringa storlek det omöjligt att utvärdera njurfunktion med traditionella metoder. Vi beskriver en fluorescerande färg njure clearance analys 1 som tillåter kvantitativ analys av zebrafisk njurfunktionen hos CKD.

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