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Sporing lægemiddelinduceret Ændringer i Receptor Post-internalisering Trafficking af Colocalizational Analysis
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Sporing lægemiddelinduceret Ændringer i Receptor Post-internalisering Trafficking af Colocalizational Analysis

Article DOI: 10.3791/52824-v • 07:48 min • July 3rd, 2015
July 3rd, 2015 •
1,2, 1,2,3
1Department of Anesthesiology and Perioperative Care, University of California Irvine, 2Department of Biomedical and Molecular Sciences, Queen's University, 3Department of Pharmacology, University of California Irvine

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Receptor menneskehandel modulerer signalering og celle lydhørhed over for ligander og er i sig selv reagerer på celle, herunder ligand-induceret signalering. Her beskriver vi en stærk og fleksibel teknik til kvantitativ vurdering af lægemiddelinduceret receptor menneskehandel hjælp immunolabeling og colocalizational analyse.

Tags

Molekylærbiologi Trafficking Receptor G-protein koblet receptor Internalisering Nedbrydning Recycling colokalisering Immuncytokemi Immunohistokemi Microscopy
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