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代谢状态的表征非人灵长类动物与静脉葡萄糖耐量试验

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Medicine

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JoVE Journal Medicine

Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test

Please note that all translations are automatically generated. Click here for the English version.

代谢状态的表征非人灵长类动物与静脉葡萄糖耐量试验

DOI:

10.3791/52895-v

•

06:59 min

•

November 13, 2016

•

Michael Staup, George Aoyagi, TeQuana Bayless, Yixin Wang, Keefe Chng

¹Cardiovascular and Metabolism Group,Crown Bioscience

Chapters

00:05Title
00:45Animal Preparation
02:44Intravenous Glucose Tolerance Test (IVGTT) Procedure
04:38Results: Representative IVGTT Glucose Clearance and Insulin Production Curves for Diabetic and Healthy Control Animals
06:17Conclusion

Summary

Automatic Translation

该协议的目的是提出一种标准方法来执行静脉内葡萄糖耐量试验（IVGTTs）评估在非人灵长类动物的血糖控制和从健康评估dysmetabolic其代谢状态。

Tags

Keywords: Intravenous Glucose Tolerance Test IVGTT Macaques Metabolic Disease Insulin Resistance Diabetes Blood Glucose Blood Sampling Dextrose Infusion Sedated Animal Pulse Oximeter Respiratory Rate Body Temperature Catheter Placement Heparin-saline Flush Fasting Blood Glucose Serum Sample Complete Blood Cell Count

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