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JoVE Journal
Immunology and Infection

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Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1
 

Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1

Article DOI: 10.3791/53046
August 24th, 2015

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Summary August 24th, 2015

The skin is one target tissue of the human pathogen herpes simplex virus type 1 (HSV-1). To explore the invasion route of HSV-1 into tissue, we established an ex vivo infection model of murine epidermal sheets which represent the outermost layer of skin.

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