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猪胫骨移植术后血管生成的动物模型
JoVE Journal
Medicine
Author Produced
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JoVE Journal Medicine
Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model
DOI:

10:31 min

August 13, 2017

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Chapters

  • 00:00Title
  • 00:16Introduction
  • 01:40Basic Principles of the Surgical Procedure
  • 03:18Presurgical Preparations
  • 03:53Harvest of a Vascularized Tibial Bone Segement (Bone VCA)
  • 06:24Orthotopic Tibial Bone VCA Reconstruction
  • 07:23Central Venous Catheter Placement
  • 07:54Postoperative Treatment and Follow Up
  • 08:46Results
  • 09:51Conclusion

Summary

Automatic Translation

目前, 任何一种带血管的复合异体移植都依赖于长期免疫抑制, 难以支持非致命的适应症。我们提出了一个新的猪胫骨 VCA 模型, 可用于研究骨 VCA 和示范使用的外科血管生成, 以维持骨骼的生存能力, 而无需长期免疫调节。

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