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JoVE Journal
Biochemistry

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Personlig peptid Arrays for påvisning af HLA Alloantibodies i organtransplantation
 
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Personlig peptid Arrays for påvisning af HLA Alloantibodies i organtransplantation

Article DOI: 10.3791/56278
September 6th, 2017

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Summary September 6th, 2017

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Uoverensstemmelser i human leukocyt antigen (HLA) sekvenser mellem organdonor og modtagende par er den største årsag til antistof-medieret afvisning i organtransplantation. Her præsenterer vi brugen af brugerdefinerede antigen arrays, der er baseret på individuelle donorer HLA sekvenser at sonde anti-donor HLA alloantibodies i orgel modtagere.

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