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Journal
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Immunology and Infection
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马达加斯加嘘声蟑螂作为非哺乳动物的替代动物模型来研究毒力、致病机制和药效
JoVE Journal
Immunology and Infection
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JoVE Journal
Immunology and Infection
The Madagascar Hissing Cockroach as an Alternative Non-mammalian Animal Model to Investigate Virulence, Pathogenesis, and Drug Efficacy
Please note that all translations are automatically generated.
Click here for the English version.
马达加斯加嘘声蟑螂作为非哺乳动物的替代动物模型来研究毒力、致病机制和药效
DOI:
10.3791/56491-v
•
12:21 min
•
November 24, 2017
•
Jennifer Chua
,
Nathan A. Fisher
,
Shane D. Falcinelli
,
David DeShazer
,
Arthur M. Friedlander
1
Bacteriology Division
,
United States Army Medical Research Institute of Infectious Diseases
,
2
Southern Research
,
3
Headquarters Division
,
United States Army Medical Research Institute of Infectious Diseases
Chapters
00:05
Title
02:08
Cockroach Preparation for Experimentation
02:58
Bacterial Culture and Drug Preparations
05:06
Assembly of the Injector
06:15
Cockroach Injections
09:22
Results: Pathogenic and Virulence Responses in Hissing Cockroaches
10:57
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
我们提出了一项协议, 利用马达加斯加嘶咝蟑螂作为替代哺乳动物模型, 以进行细菌的毒力, 发病机制, 药物毒性, 药物功效, 和先天免疫反应研究。
Tags
Madagascar Hissing Cockroach
Animal Model
Gromphadorhina
Microbiology
Host-pathogen Interactions
Microbial Pathogenesis
Virulence Factors
Drug Efficacy
Burkholderia
Galleria Waxworm
Temperature Acclimation
Injection Procedure
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