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JoVE Journal
Immunology and Infection

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The Insect Galleria mellonella as a Powerful Infection Model to Investigate Bacterial Pathogenesis
 

The Insect Galleria mellonella as a Powerful Infection Model to Investigate Bacterial Pathogenesis

Article DOI: 10.3791/4392
December 11th, 2012

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Summary December 11th, 2012

Oral and intra haemocolic infection of larvae of the greater wax moth Galleria mellonella is described. This insect can be used to study virulence factors of entomopathogenic as well as mammalian opportunistic bacteria. Rearing of the insects, methods of infection and examples of in vivo analysis are described.

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