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Trans-trumhinna Drug Delivery för behandling av ototoxicitet
JoVE Journal
Medicine
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JoVE Journal Medicine
Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity
DOI:

09:52 min

March 16, 2018

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Chapters

  • 00:04Title
  • 00:57Auditory Brainstem Response (ABR)
  • 01:59Trans-tympanic Injection
  • 03:55Cochlea Dissection and Decalcification
  • 04:38Cryosectioning and Immunohistochemistry
  • 07:37Results: Representative Effects of Trans-tympanic Drug/Biologic Delivery to the Rat Cochlea
  • 09:20Conclusion

Summary

Automatic Translation

Vi presenterar en teknik för lokaliserade administrering av läkemedel genom trans-trumhinna rutten in i cochlean. Drogen leverans via denna väg skulle inte störa mot cancer effekten av de kemoterapeutiska läkemedel såsom cisplatin.

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