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Assessing Activity-based Anorexia in Mice

Assessing Activity-based Anorexia in Mice

Article DOI: 10.3791/57395-v 08:26 min May 14th, 2018
May 14th, 2018



Mice individually housed with a running wheel while given limited access to food develop reductions in food consumption and increase activity on the running wheel. This experimental phenomenon is called activity-based anorexia. This paradigm provides an experimental tool for studying the neurobiology and behaviors underlying aspects of anorexia nervosa.


Keywords: Anorexia Nervosa Activity-based Anorexia Mouse Model Neurobiology Eating Disorders Running Wheel Food Restriction Behavioral Assessment
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