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JoVE Journal
Behavior

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Using the Activity-based Anorexia Rodent Model to Study the Neurobiological Basis of Anorexia Nervosa
 

Using the Activity-based Anorexia Rodent Model to Study the Neurobiological Basis of Anorexia Nervosa

Article doi: 10.3791/52927
October 22nd, 2015

Summary October 22nd, 2015

Here we present a protocol to induce activity-based anorexia (ABA) in female adolescent mice. ABA is a condition of hyperactivity evoked by imposing food restriction on rodents with access to a running wheel. This phenomenon is being used as a model to study the underlying neurobiology of anorexia nervosa.

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