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Journal / Chemistry / Regioselective O-Glycosylation Nucleosides 통해 는…
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JoVE Journal Chemistry
Regioselective O-Glycosylation Nucleosides 통해 는 임시 2', 3'-Diol 보호 Boronic 에스테 르에 의해이 당 Nucleosides의 합성에 대 한의
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Regioselective O-Glycosylation Nucleosides 통해 는 임시 2', 3'-Diol 보호 Boronic 에스테 르에 의해이 당 Nucleosides의 합성에 대 한의

Article DOI: 10.3791/57897-v • 08:46 min • July 26th, 2018
July 26th, 2018 •
1, 1, 1, 1,2
1Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2Imaging Frontier Center, Tokyo University of Science

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여기, 우리 제시이 당 nucleosides의 합성에 대 한 프로토콜을 통해 ribonucleosides의 regioselective Oglycosylation에 의해의 임시 보호 그들의 2', 3'-diol moieties 주기적 boronic 에스테 르를 이용 하 여. 이 메서드는 아데노신, guanosine, cytidine, uridine, 5-methyluridine, 5-fluorouridine을 주고 해당이 당 nucleosides 등 여러 보호 nucleosides에 적용 됩니다.

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화학 문제 137,이 당 nucleosides Oglycosylation ribonucleosides 임시 보호 thioglycosides 순환 boronic 에스테 르
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