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The Generation of Closed Femoral Fractures in Mice: A Model to Study Bone Healing
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The Generation of Closed Femoral Fractures in Mice: A Model to Study Bone Healing

The Generation of Closed Femoral Fractures in Mice: A Model to Study Bone Healing

DOI:
10.3791/58122-v

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05:53 min

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August 16, 2018

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, , ,
1Department of Anatomy and Cell Biology,Indiana University School of Medicine

Chapters

  • 00:04Title
  • 00:42Femoral Fracture Induction
  • 04:06Results: Representative Healing Progression Monitoring
  • 05:09Conclusion

Summary

Automatic Translation

Automatic Translation

The murine closed femoral fracture model is a powerful platform to study fracture healing and novel therapeutic strategies to accelerate bone regeneration. The goal of this surgical protocol is to generate unilateral closed femoral fractures in mice using an intramedullary steel rod to stabilize the femur.

Tags

Keywords: Closed Femoral FractureBone HealingMouse ModelSurgical ProcedureMinimally InvasiveStandardized FractureThree-point BendingFracture GeometryFracture Healing Research

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