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The Generation of Closed Femoral Fractures in Mice

The Generation of Closed Femoral Fractures in Mice: A Model to Study Bone Healing

Article DOI: 10.3791/58122 05:53 min August 16th, 2018
August 16th, 2018



The murine closed femoral fracture model is a powerful platform to study fracture healing and novel therapeutic strategies to accelerate bone regeneration. The goal of this surgical protocol is to generate unilateral closed femoral fractures in mice using an intramedullary steel rod to stabilize the femur.



Closed Femoral Fractures Mice Model Bone Healing Research Fracture Healing Therapeutic Strategies Minimally Invasive Procedure Standardized Fractures Surgical Procedure Sedation Anesthetized Mouse Disinfect Skin Heating Pad Sterile Surgical Drape Knee Incision Patella Displacement Medullary Canal X-ray Imaging
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