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Synthese van 68Ga ijzeroxide Core-doped nanodeeltjes voor Dual Positron emissie tomografie / (T-1) magnetische resonantie Imaging
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Synthese van 68Ga ijzeroxide Core-doped nanodeeltjes voor Dual Positron emissie tomografie / (T-1) magnetische resonantie Imaging

Article DOI: 10.3791/58269-v • 07:26 min • November 20th, 2018
November 20th, 2018 •
1, 2, 1, 3
1Nanobiotechnology, Molecular Imaging and Metabolomics Lab, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 2CIC biomaGUNE and CIBER de Enfermedades Respiratorias (CIBERES). Ikerbasque, Basque Foundation for Science, Universidad Complutense de Madrid (UCM), 3Advanced Imaging Unit, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), CIBER de Enfermedades Respiratorias (CIBERES)

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Hier presenteren we een protocol te verkrijgen68Ga ijzeroxide core-doped nanodeeltjes via snel magnetron-gedreven synthese. De methodologie maakt PET / (T-1) MRI nanodeeltjes met radiolabeling efficiëntie hoger dan 90% en radiochemische zuiverheid van 99% in een 20-min-synthese.

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Biologie kwestie 141 ijzeroxide nanodeeltjes 68Ga positron emissie tomografie magnetische resonantie beeldvorming magnetron synthese citroenzuur
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