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Fabrikation af anisotrope polymere kunstige Antigen præsentere celler for CD8 + T-celle aktivering
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Fabrikation af anisotrope polymere kunstige Antigen præsentere celler for CD8 + T-celle aktivering

Article DOI: 10.3791/58332-v • 10:16 min • October 12th, 2018
October 12th, 2018 •
*1, *1, 1, 2
1Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Johns Hopkins University School of Medicine, 2Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Ophthalmology, Oncology, Neurosurgery, Materials Science and Engineering, Chemical and Biomolecular Engineering, and the Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine
* These authors contributed equally

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Vi præsenterer her, en protokol for at hurtigt og reproducerbar generere biologisk inspirerede, biologisk nedbrydelige articifical antigen præsentere celler (aAPC) med afstemmelige størrelse, form og overflade protein præsentation for T-celle ekspansion ex vivo eller in vivo .

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Miljøvidenskab spørgsmål 140 aAPC immunoengineering polymer anisotrope partikel figur
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