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Tillverkning av anisotropisk polymera konstgjorda antigenpresenterande celler CD8 + T Cell aktivering
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Tillverkning av anisotropisk polymera konstgjorda antigenpresenterande celler CD8 + T Cell aktivering

Article DOI: 10.3791/58332-v • 10:16 min • October 12th, 2018
October 12th, 2018 •
*1, *1, 1, 2
1Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Johns Hopkins University School of Medicine, 2Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Ophthalmology, Oncology, Neurosurgery, Materials Science and Engineering, Chemical and Biomolecular Engineering, and the Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine
* These authors contributed equally

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Här presenterar vi ett protokoll för att snabbt och reproducibly generera biologiskt inspirerad, biologiskt nedbrytbar dagsljus antigenpresenterande celler (aAPC) med avstämbara storlek, form och yta protein presentation för T-cell expansion ex vivo eller in vivo .

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