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Lentiviral vektor-medieret genterapi af hepatocytter Ex Vivo til autolog Transplantation hos svin
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Lentiviral vektor-medieret genterapi af hepatocytter Ex Vivo til autolog Transplantation hos svin

Article DOI: 10.3791/58399-v • 09:54 min • November 4th, 2018
November 4th, 2018 •
1,2, 1, 3, 1, 1, 1, 1, 1, 1, 1, 1,2,4
1Department of Surgery, Mayo Clinic, 2Midwest Fetal Care Center, Children's Hospitals and Clinics of Minnesota, 3Department of Surgery, Johns Hopkins, 4Pediatric Surgical Associates

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Denne protokol er beregnet til at beskrive svin hepatocyt isolation og ex vivo gen levering for at helbrede modeller af metaboliske sygdomme via autologe celler transplantation. Selv om netop denne model har unikke fordele, der favoriserer succesfulde terapi, er ansøgningen en relevant foundation til at løse flere sygdomme og indikationer.

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Medicin sag 141 Gene Therapy Lentiviral vektor hepatocyt Isolation gris kirurgisk model autolog Transplantation medfødt fejl i metabolisme
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