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1Department of Chemistry,Brooklyn College, The City University of New York, 2Ph.D. Program in Chemistry,The Graduate Center of The City University of New York, 3Ph.D. Program in Biochemistry,The Graduate Center of The City University of New York, 4Department of Genetics and Genomic Sciences,Icahn School of Medicine at Mount Sinai, 5Women’s Health Research Institute,Icahn School of Medicine at Mount Sinai, 6Laboratory for Translational Research,Western Connecticut Health Network
Chapters
- 00:04Title
- 00:35Synthesis of Oleic Acid-Platinum(II) Conjugate
- 02:41Preparation of Unmodified and Fluorescein Isothiocyanate (FITC)-Modified Lysine-Tyrosine-Phenylalanine (KYF) Tripeptide
- 05:59Synthesis of FITC-KYF-Stabilized or KYF-Stabilized Nanoemulsion with Oleic Acid-Pt(II) Cores (FITC-KYF-Pt-NE or KYF-Pt-NE)
- 08:03Results: KYF-Pt-NE and FITC-KYF-Pt-NE Characterization
- 09:43Conclusion
Det här protokollet beskriver en effektiv metod för att syntetisera en nanoemulsion av en oljesyra acids-platinum(II) konjugat stabiliserad med en lysin-tyrosin-fenylalanin (KYF) tripeptid. De nanoemulsion formerna under milda syntetiska förhållanden via självmontering av KYF och konjugat.
