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Chapters
- 00:04Title
- 00:39Tumor Tissue Processing for Mouse Implantation
- 02:42Tumor Implantation and Injection in Mice
- 04:07Tumor Harvesting for Banking Tissue, Reimplantation, and Experiment Characterization
- 05:30Results: Analysis of Melanoma Patient-Derived Xenograft Models
- 06:18Conclusion
Patient afledte xenograft (PDX) modeller mere robust rekapitulere melanom molekylære og biologiske egenskaber og er mere forudsigende for terapi respons sammenlignet med traditionelle plast vævskultur-baserede assays. Her beskriver vi vores standard Operations protokol for etablering af nye PDX modeller og karakterisering/eksperimenter af eksisterende PDX modeller.
