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Journal / Bioengineering / Humane neurale Organoider til at studere…
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Bioengineering

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JoVE Journal Bioengineering
Humane neurale Organoider til at studere hjernekræft og neurodegenerative sygdomme
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Humane neurale Organoider til at studere hjernekræft og neurodegenerative sygdomme

Article DOI: 10.3791/59682-v • 09:36 min • June 28th, 2019
June 28th, 2019 •
*1, *2, 2, 3, 3, 4, 5, 4, 2
1Laboratory of Tumor Immunology, Translational Research Center in Onco-Hematology, Department of Internal Medicine Specialties, Faculty of Medicine, University of Geneva, 2Department of Pathology and Immunology, University Medical Center, University of Geneva, 3Laboratory of Toxicology and Therapeutic Drug Monitoring, Geneva University Hospitals, 4Tissue Engineering Laboratory, Hepia/HES-SO, University of Applied Sciences Western Switzerland, 5Laboratory of Experimental cell therapy, Department of Diagnostics, Geneva University Hospitals
* These authors contributed equally

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Denne undersøgelse introducerer og beskriver protokoller til at udlede to specifikke humane neurale organoider som en relevant og præcis model til at studere 1) menneskelig glioblastoma udvikling inden for humane neurale organoider udelukkende hos mennesker og 2) neuron dopaminerge differentiering genererer en tredimensionel organoid.

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Bioteknik neurale organoid glioblastoma multiforme kræft stamceller humane embryonale stamceller dopaminerge neuroner neurodegenerative sygdomme
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