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JoVE Journal
Immunology and Infection

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葡萄糖-6-磷酸异构酶(G6PI)诱导RA小鼠中iNKT细胞的采用免疫治疗
 

葡萄糖-6-磷酸异构酶(G6PI)诱导RA小鼠中iNKT细胞的采用免疫治疗

Article doi: 10.3791/60048
January 31st, 2020

Summary January 31st, 2020

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该协议使用G6PI混合肽构建类风湿关节炎模型,更接近CD4+T细胞和细胞因子中的人类类风湿性关节炎模型。高纯度不变天然杀伤性T细胞(主要是iNKT2),具有特定的表型和功能,通过体内诱导和体外纯化获得,用于采用免疫治疗。

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