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Murine kirurgisk model af aktuel elastase induceret faldende Thoracic aorta aneurisme
JoVE Journal
Medicine
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JoVE Journal Medicine
Murine Surgical Model of Topical Elastase Induced Descending Thoracic Aortic Aneurysm
DOI:

00:08 min

August 24, 2019

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Chapters

  • 00:04Title
  • 00:33Mouse Position Preparation
  • 01:09Thorax Entry
  • 02:24Aortic Exposure
  • 03:04Elastase Exposure
  • 03:48Chest Closure and Recovery
  • 04:28Thoracic Aortic Aneurysm (TAA) Harvest
  • 06:58Results: Representative Effects of TAA Formation
  • 07:54Conclusion

Summary

Automatic Translation

Vi beskriver en kirurgisk protokol til konsekvent at inducere robust nedadgående thorax aorta aneurismer i mus. Proceduren involverer venstre thoracotomi, thorax aorta eksponering, og placering af en svamp gennemblødt i Porcin pancreas elastase på aorta væggen.

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